Summary of SATB2 (FLJ21474, KIAA1034) expression in human tissue. Selective nuclear expression in large intestine and subsets of neuronal cells in brain.

Mouse monoclonal SATB2 antibody [SATBA4B10] - C-terminal. Validated in WB, IP, ICC and tested in Mouse, Human. Cited in 164 publication(s). Independently reviewed in 15 review(s). Immunogen…

IHC overlap among different 15 Sep 2015 (D) SATB2 immunostaining of a P0 WT cortex. tracing from the cerebral peduncle or thalamus with SATB2 immunohistochemistry (Fig. 1). 29 Nov 2016 Immunostaining for Satb2 of sagittal brain sections from adult mice.

Western blot protocols. Click here to view the general protocols. Datasheets and documents. Immunohistochemical Expression of CDX2 and SATB2 in Primary Breast Carcinomas Assarzadegan, Naziheh MD; Gonzalo, David H. MD; Leon, Marino E. MD; Asirvatham, Jaya R. MD Author Information SATB2 : Immunohistochemistry on sections of paraffin-embedded tissue.( Cartun RW, Taylor CR, Dabbs DJ: Techniques of immunohistochemistry: Principles, pitfalls, and Immunohistochemistry analysis in human rectum and skeletal muscle tissues using AMAb90635 antibody. Corresponding SATB2 RNA-seq data are presented for the same tissues. Compare Anti-SATB2 Immunohistochemistry Antibody Products from leading suppliers on Biocompare. View specifications, prices, citations, reviews, and more.

Summary of SATB2 (FLJ21474, KIAA1034) expression in human tissue. Selective nuclear expression in large intestine and subsets of neuronal cells in brain.

SATB2 stains colonic and osteogenic cells and their neoplasms. Specimen Requirements.

SATB2 and PAX8 expression was further evaluated in ovarian tumors from an international cohort of 2876 patients where immunohistochemistry is not routinely carried out,

The cancer tissue page shows antibody staining of the protein in 20 different cancers. Anti-SATB2 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. SATB2 immunohistochemistry was performed on 266 NNs, including lung small cell carcinomas (n = 39) and carcinoids (n = 30), bladder (n = 21) and prostate (n = 31) small cell carcinomas, and gastrointestinal (GI)/pancreatic NNs of various primary sites (n = 145) consisting of well‐differentiated neuroendocrine tumours (WDNET)s (n = 124) and poorly differentiated neuroendocrine carcinomas 2016-09-01 SATB2 is commonly expressed in osteosarcomas.

Abstract. To investigate layer-specific molecule expression in human developing neocortices, we performed immunohistochemistry of the layer-specific markers (TBR1, FOXP1, SATB2, OTX1, CUTL1, and CTIP2), using frontal neocortices of the dorsolateral precentral gyri of 16 normal controls, aged 19 gestational weeks to 1 year old, lissencephalies of 3 Miller–Dieker syndrome (MDS) cases, 2 X Immunohistochemical Expression of CDX2 and SATB2 in Primary Breast Carcinomas Assarzadegan, Naziheh MD; Gonzalo, David H. MD; Leon, Marino E. MD; Asirvatham, Jaya R. MD Author Information SATB2 antibody has been identified as a tissue-specific protein when screening protein expression patterns in human and cancerous tissues, with expression restricted to the lower gastrointestinal tract. SATB2 in combination with CK20 and Cadherin 17 could identify almost all colorectal carcinomas, including poorly differentiated colorectal carcinomas.
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Special AT-rich binding protein 2 (SATB2) immunohistochemistry (IHC) has high sensitivity and specificity for colorectal adenocarcinoma (CRC), but data on its expression in specific subsets of pulmonary, gastric, small bowel, and pancreatobiliary adenocarcinomas (ADCAs) are relatively limited or discordant. A retrospective analysis of 146 and a prospective cohort of 557 colorectal carcinoma patients both showed that decreased SATB2 expression by immunohistochemistry was associated with a worse prognosis, as well as decreased sensitivity to chemotherapy and radiation, for colonic but not rectal carcinoma. 11,12 Mansour et al 13 showed a tumor-suppressive function for SATB2 in vitro and a potential mechanism of this suppression via inactivation of tumor-promoting factor ERK5. SATB2 is commonly expressed in osteosarcomas. Although apparently being a valuable diagnostic marker for differentiating between small cell osteosarcoma (SCO) and other small round cell tumors of bone, for instance Ewing sarcoma family of tumors (ESFT), it has not been tested in a large series of ES ….

SATB2 is a nuclear matrix attachment region-binding transcription factor with developmental role in craniofacial, neural, and osteoblastic differentiation. Several publications have documented SATB2 expression in the epithelium of the lower gastrointestinal tract (appendix, colon, and rectum). 2018-09-07 2016-02-15 SATB2 immunohistochemistry was scored for extent (%) and intensity (0-3+) with an H-score calculated.
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SATB2 and TLE1 Expression in BCOR-CCNB3 (Ewing-like) Sarcoma, Mimicking Small Cell Osteosarcoma and Poorly Differentiated Synovial Sarcoma Creytens, David MD, PhD *,† Author Information

SATB2 is a sensitive marker for colorectal adenocarcinomas. No study has investigated its diagnostic utility in metastatic Krukenberg tumors (MKTs) of the ovary.Here we performed immunohistochemical staining SATB2 in 70 MKTs of various origins (stomach 27, colorectum 13, appendix 20 including 19 metastatic adenocarcinomas ex goblet cell carcinoids [AdexGCC] and 1 conventional poorly SATB2 Positive Control Slides, Product No. 384S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). Physical form Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide. Preparation Note Antibody information for antibodies HPA001042, HPA029543, CAB023669, CAB062562, CAB067751, CAB068229, CAB068230 and CAB068231 used in analysis of ENSG00000119042 / SATB2 … 2019-11-26 2017-09-01 SATB2 immunohistochemistry was scored for extent (%) and intensity (0–3+), with an H‐score being calculated. SATB2 was expressed by 96% of rectosigmoid NETs, 79% of appendiceal NETs, and only 7% of other well‐differentiated neoplasms (P < 0.0001). Expression of SATB2 (FLJ21474, KIAA1034) in cancer tissue.